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Silica Nanoparticles and Polyethyleneimine (PEI)Mediated ...

Silica Nanoparticles and Polyethyleneimine (PEI)Mediated Functionalization: A New Method of PEI Covalent Attachment for siRNA Delivery Applications Article in Bioconjugate Chemistry 24(12 ...

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Mesoporous silica nanoparticles with lactosemediated ...

Mesoporous silica nanoparticles with lactosemediated targeting effect to deliver platinum(IV) prodrug for liver cancer therapy Zigui Wang , a b Peng Wu , c Zhilong He , d Hongyan He , a Weifeng Rong , e Jizhen Li , * c Dongfang Zhou * a and Yubin Huang a

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Kupffer cellmediated hepatic injury induced by silica ...

Silica nanoparticles (SiO 2 NPs) have been shown to exert cytotoxic effects in hepatocytes and to cause liver injury. In the liver, Kupffer cells (KCs), as the resident macrophages, play an important role in the normal physiology and homeostasis of the liver.

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APTAMER MEDIATED CYTOTOXICITY OF DRUG CARRYING …

mesoporous silica nanoparticles can be utilized as a targeted drug delivery system. This study aims to assess the targeting ability, localization, and cytotoxicity of drug loaded ... we assessed the effect of aptamer mediated silica nanoparticle usage on efficiency of drug delivery and cytotoxic effect in comparison to free paclitaxel. ...

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Silica Nanoparticlesmediated Stable Genetic ...

Silica Nanoparticlesmediated Stable Genetic Transformation in Nicotiana tabacum FU Yuqin 1, LI Luhua1, WANG Hui1, JIANG Yuan1, LIU Huijing1, CUI Xiyan1, WANG Piwu 1* and LÜ Changli2* 1. College of Life Science, Jilin Agricultural University, Changchun 130018, P. R. China; 2.

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Fumed silica nanoparticle mediated biomimicry for optimal ...

Fumed silica nanoparticle mediated biomimicry for optimal cellmaterial interactions for artificial organ development. Achala De Mel, Bala Ramesh, David J. Scurr, Morgan R. Alexander, George Hamilton, Martin Birchall, Alexander M. Seifalian ... Fumed silica nanoparticle mediated biomimicry for optimal cellmaterial interactions for artificial ...

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Gold Functionalized Mesoporous Silica Nanoparticle ...

Gold Functionalized Mesoporous Silica Nanoparticle Mediated Protein and DNA Codelivery to Plant Cells Via the Biolistic Method The synthesis and characterization of a gold nanoparticle functionalized mesoporous silica nanoparticle (AuMSN) platform for codelivery of proteins

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In Vitro Study of ReceptorMediated Silica Nanoparticles ...

transport efficiency of lactoferrin conjugated silica nanoparticle was observed for 25 nm diameter particles. This receptormediated transcytosis of Si NPs across the cerebral endothelial cells can be employed to deliver drugs and imaging probes to the brain. KEYWORDS: silica nanoparticles, blood−brain barrier, receptor, lactoferrin, transcytosis

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Mesoporous Silica NanoparticleMediated Intracellular Cre ...

Mesoporous Silica NanoparticleMediated Intracellular Cre Protein Delivery for Maize Genome Editing via loxP Site Excision, Susana MartinOrtigosa , David J. Peterson , Justin S. Valenstein , Victor S.Y. Lin , Brian G. Trewyn , L. Alexander Lyznik , Kan Wang

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Silica nanoparticles to control the lipasemediated ...

TY JOUR. T1 Silica nanoparticles to control the lipasemediated digestion of lipidbased oral delivery systems. AU Tan, Angel. AU Simovic, Spomenka

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Cellular Fate of a Modular DNA Delivery System Mediated by ...

Cellular Fate of a Modular DNA Delivery System Mediated by Silica Nanoparticles Richard A. Gemeinhart,* Dan Luo,‡ and W. Mark Saltzman† School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, New York 148505201

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Silica nanoparticles inhibit macrophage activity and ...

Silica nanoparticles inhibit macrophage activity and angiogenesis via VEGFR2mediated MAPK signaling pathway in zebrafish embryos. ... Silica nanoparticles (SiNPs) as the most largelyused nanomaterials, ... we found that SiNPs could inhibit the macrophage activity and angiogenesis via VEGFR2mediated MAPK signaling pathway in zebrafish embryos ...

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[Full text] Amorphous silica nanoparticles trigger ...

Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen speciesmediated MAPK/Bcl2 and PI3K/Akt/mTOR signaling Caixia Guo,1,2 Man Yang,2,3 Li Jing,2,3 Ji Wang,2,3 Yang Yu,2,3 Yang Li,2,3 Junchao Duan,2,3 Xianqing Zhou,2,3 Yanbo Li,2,3 Zhiwei Sun2,3 1Department of Occupational and Environmental Health, School of Public Health ...

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Membrane Fusion Mediated Intracellular Delivery of Lipid ...

Membrane Fusion Mediated Intracellular Delivery of Lipid Bilayer Coated Mesoporous Silica Nanoparticles. Authors. Jian Yang, ... hampering clinical applications. In this contribution cuboidal mesoporous silica nanoparticles (MSNs) containing diskshaped cavities with a large pore diameter (10 nm) are studied as a protein delivery vehicle using ...

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LigandMediated TiO2 Functionalization of Silica ...

Introduction: Post synthesis titania (TiO 2) functionalization of silica nanoparticles (SNPTs) is a facile, yet robust process to obtain a stable system capable of binding natural products of therapeutic interest, such as , these particles are not efficient in utilizing all of the TiO 2sites due to clustering or layer formation, and may not be selective in what they bind.

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Theoretical study on femtosecond laser optical breakdown ...

It is suggested that water could be ionized by aluminum/silica (core/shell) nanostructure during femtosecond laser exposures without nanoparticles consumption. This model could increase understanding of the aluminum nanoparticlemediated optical breakdown in water.

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Apoptosis induction by silica nanoparticles mediated ...

Silica nanoparticles are increasingly utilized in various applications including agriculture and medicine. In vivo studies have shown that liver is one of the primary target organ of silica nanoparticles. However, possible mechanisms of hepatotoxicity caused by silica nanoparticles still remain ...

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US20130185823A1 Mesoporous silica nanoparticlemediated ...

Transient gene expression is a powerful tool for plant genomics studies. Recently, the use of nanomaterials has drawn great interest. Delivery with mesoporous silica nanoparticles (MSNs) has many advantages. We used surfacefunctionalized MSNs to deliver and express foreign DNA in Arabidopsis thaliana root cells without the aid of particle bombardment.

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